Friday, February 9, 2007

Let's Talk Sleep "Abstract Listing Pick of the Week"-- Presiposing factors of restless legs syndrome in pregnancy

I found this paper especially interesting because it correlates to the conversation I had witn Dr. Meir Kryger on the Let's Talk Sleep Radio program that aired earlier this week. Dr. Kryger discussed various aspects of sleep in women, and spoke about RLS during pregnancy. You can hear the podcast at no charge on iTunes or at , and you do not need an iPod to listen. (One listener from Israel I was talking with the other day said he downloads the MP3 files onto CD and listens in his car to and from work).

Predisposing factors of restless legs syndrome in pregnancy.
Mov Disord. 2007 Feb 6; Tunç T, Karadağ YS, Doğulu F, Inan LE

The occurrence of restless legs syndrome in pregnancy is well known. However, the mechanism of this association is unclear. In this study, we aimed to identify the factors that predispose women to have restless legs syndrome during pregnancy. A total of 146 pregnant women were included in the study. Patients were asked questions regarding demographic characteristics, complications of pregnancy, medical therapy (vitamin and iron intake), sleep disorders, muscle cramps, and excessive daytime sleepiness. Electroneurography, routine blood biochemistry tests, complete blood count, and thyroid function tests were performed and vitamin B12, folic acid, serum iron, iron-binding capacity, ferritin, iron saturation, prolactin, estradiol, and progesterone were measured. Of the participants, 38 were diagnosed as having restless legs syndrome. In women with restless legs syndrome, additional medical problems, night cramps, and excessive daytime sleepiness were more frequent. In women without restless legs syndrome, serum hemoglobin levels were significantly higher and the use of supplemental iron or vitamins was greater. Among the women with restless legs syndrome, progesterone levels were slightly higher but this difference was not statistically significant. In summary, in this study, lower hemoglobin levels and supplementation deficits of iron and vitamins were found be the risk factors for restless legs syndrome in pregnancy.

For the full text, contact the journal publisher directly.

Have a great weekend!


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